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目的探讨临床腋窝淋巴结阴性(cN0)乳腺癌患者全腋窝淋巴结清扫应用的可行性。方法cN0女性乳腺癌患者180例分为两组,分别行乳腺癌改良根治I式100例(M组)和Kodama改良根治术80例(K组),比较两组的治疗效果。结果腋窝淋巴结清扫结果:M组人均11.2枚,明显少于K组的15.8枚(P<0.05);K组锁骨下淋巴结总数231枚,阳性3枚。M组和K组淋巴结转移者分别为18例和21例。两组术后并发症及5年生存率均无显著性差异。结论Kodama改良根治术可安全、有效的应用于cN0乳腺癌的手术治疗。
Objective To investigate the feasibility of axillary lymph node dissection in patients with clinical axillary lymph node-negative (cN0) breast cancer. Methods One hundred and eighty women with cN0 female breast cancer were divided into two groups. One group (100 cases) of modified radical mastectomy (group M) and another 80 cases of modified radical mastectomy (group K) were treated respectively. The curative effect was compared between the two groups. Results The result of axillary lymph node dissection was 11.2 in M group, which was significantly lower than 15.8 in K group (P <0.05). There were 231 clavicular lymph nodes in K group with 3 positives. M and K lymph node metastasis were 18 cases and 21 cases. There were no significant differences in postoperative complications and 5-year survival rate between the two groups. Conclusion Kodama modified radical mastectomy can be safely and effectively applied to the surgical treatment of cN0 breast cancer.