本文对３１８份阳性动物血清进行研究，首次报道了放射免疫沉淀试验（ＲＩＰ）检测鼠疫Ｆ１抗体中发生的前滞现象、前滞率及前滞的稀释度范围等实验结果。３１８份阳性血清在１∶１０～１∶８０稀释度范围内有８５份出现前滞现象，前滞率为２６７３％，其中１∶１０～１∶４０稀释度出现前滞８１份，占９５２９％，稀释度在１∶８０仅４份出现前滞，占４７１％，１∶８０以上的稀释度基本不发生前滞或只发生部分前滞，其结合率均比阴性对照高３倍以上。因此，建议对常规的ＲＩＰ检测鼠疫Ｆ１抗体的实验方法进行改进，在筛检试验中将１∶１０省去，单独对１∶１００进行检测，这不但节省时间、人力、物力及财力，而且能获得同等的检测效果 In this paper, 318 positive animal sera were studied, the first report of the radioimmunoprecipitation (RIP) test for the detection of plague F1 antibody occurred in the pre-stagnation, pre-delay and delay the range of dilution and other experimental results. There were 85 pre-lag appearances in 318 positive sera from 1:10 to 1:80, with a pre-hysteresis of 2673%, of which 81 pre-lagged at 1:10 to 1:40, accounting for 9529%, dilution in 1:80 only 4 copies of the pre-stagnation, accounting for 471%, 1:80 or more dilution basically no pre-delay or partial pre-delay, the binding rate than the negative control 3 times more high. Therefore, it is suggested to improve the experimental method of conventional RIP to test the F1 antibody against plague, which will be eliminated 1:10 in the screening test and tested alone at 1: 100, which will not only save time, manpower, material and financial resources but also Get the same test results