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探讨肝硬化患者胆结石发生率及其与肝功能Child—pugh分级、血清总胆汁酸含量的关系。方法:115例住院肝硬化患者,用B超或CT检查确定有无胆结石及胆石的部位,应用酶法测定其血清总胆汁酸(TBA)、总胆红素(TBIU、白蛋白(ALB)的含量,并与102例非肝病的胃十。指肠疾病患者比较。结果:115例肝硬化患者胆结石发生率显著高于非肝病对照组(P<0.05),肝损愈重,并发胆石率愈高。肝硬化并胆石组血清TBA、TBIL明显高于非胆石组,ALB明显低于非胆石组(P<0.05)。结论:肝硬化患者胆结石发生率增高,与肝功能障碍造成的TBA、TBIL、ALB代谢紊乱密切相关。
To investigate the incidence of gallstone in patients with cirrhosis and its relationship with Child-pugh liver function classification, serum total bile acid content. Methods: One hundred and seventy patients with cirrhosis of the liver were enrolled in this study. The presence of gallstones and gallstones was determined by B-mode ultrasonography or CT. Serum total bile acid (TBA), total bilirubin (TBIU, albumin (ALB) , And compared with 102 patients with non-hepatic diseases of gastroduodenal disease.Results: The incidence of gallstones in 115 patients with cirrhosis was significantly higher than that of non-liver disease control group (P <0.05) (P <0.05) .Conclusion: The incidence of gallstone in patients with cirrhosis is higher than that in non-gallstone group (P <0.05) Dysfunction caused by TBA, TBIL, ALB metabolic disorders are closely related.