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多发性肌炎 (ｐｏｌｙｍｙｏｓｉｔｉｓ,ＰＭ)是一组常见的自身免疫性炎性肌病。已有研究表明 ,ＰＭ的发病机制与Ｔ细胞异常活化有关。Ｔ细胞的活化需要两个刺激信号 :Ｔ细胞受体 /白细胞分化抗原 3(ＴＣＲ/ＣＤ3)复合物与抗原提呈细胞 (ＡＰＣ)上的组织相容性抗原 Ⅱ (ＭＨＣ
Polymyositis (PM) is a common group of autoimmune inflammatory myopathies. Studies have shown that the pathogenesis of PM is related to the abnormal activation of T cells. T cell activation requires two stimulatory signals: T cell receptor / leukocyte differentiation antigen 3 (TCR / CD3) complex and antigen presenting cell (APC) on the histocompatibility antigen Ⅱ (MHC