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酮康唑应用于临床以来,证明口服吸收好,疗效高,副作用小,既能治疗各种浅部真菌病,又能治疗深部真菌病,是目前较好、较有前途的广谱抗真菌药。现将1978~1984年所查到的文献资料综述如下: 一、适应证和禁忌症(一)治疗体表和体内真菌病,包括1.皮癣菌或酵母菌对皮肤、指甲的感染;皮肤真菌病、花斑癣、阴道念珠菌病、慢性粘膜念珠菌病、甲癣。2.口腔(鹅口疮、传染性口角炎)、肠胃道的酵母菌感染。3.系统性真菌感染,如系统性念珠菌病、副球孢子菌病、球孢子菌病及组织胞浆菌病。
Since the clinical application of ketoconazole, it has been proved that oral absorption is good, the curative effect is high, and the side effects are small. It can not only treat various superficial mycoses and treat deep mycoses, but also is a good and promising broad-spectrum antifungal agent . The literature data from 1978 to 1984 are summarized as follows: First, the indications and contraindications (a) the treatment of body surface and body fungal diseases, including 1. dermatophytes or yeast infection of the skin, nails; skin Mycosis, tinea versicolor, vaginal candidiasis, chronic mucosal candidiasis, onychomycosis. 2. Oral (thrush, contagious angular cheilitis), gastrointestinal yeast infection. 3. Systematic fungal infections, such as systemic candidiasis, vice coccidioidomycosis, coccidioidomycosis and histoplasmosis.