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多原发恶性肿瘤是指同一宿主的单个或多个器官同时或先后发生两个或两个以上原发性恶性肿瘤．近１０多年来由于检治癌症的仪器Ｂ超、ＣＴ、ＭＲＩ的普遍应用到临床上，癌症的早期发现、早期治疗有了明显提高，还因患者寿命延长，故对多原发癌的发现也随之增加． 本文报告５例相关泌尿系的多原发癌：男性４例，女性１例；年龄从４６岁～７４岁，平均６２岁，第一原发癌诊疗后至第二原发癌出现为３个月～８年，平均５８．２个月，其中１例在第二原发癌治疗后，２年再生第三原发癌．第一原发癌为肾透明细胞癌、膀胱移行细胞癌、右肾上腺无功能皮质癌，在治疗后的５年、６年、３个月出现结肠癌，胃中分化腺癌及食道上段鳞癌；第一原发癌为左乳腺癌、胃癌在治疗后的５年、８年出现右肾盂癌，膀胱乳头状癌． 本文还讨论了多原发癌病人与机体免疫缺陷，化疗后药物诱发，放疗后引起放射性二重病及年老病人机体抵抗力，免疫力下降有关．对于多原发癌的病人，由于癌肿互为独立性，积极的手术治疗，可使病人延长生命，提高生活质量．证实陈氏报告第一原发癌为消化道癌而后发生尿路上皮癌者预后比先发生尿路上皮癌后发生消化道癌者好．临床医生在诊断、治疗及追问病史中，应警惕第二原发癌的存在；对无法手术的病例?
Multiple primary malignancies refer to the simultaneous or sequential occurrence of two or more primary malignancies in one or more organs of the same host. Over the past 10 years due to the detection of cancer equipment B ultrasound, CT, MRI is widely used in clinical, early detection of cancer, early treatment has been significantly improved, but also because of patients with longer life expectancy, so the discovery of multiple primary cancer Increase accordingly. This article reports five cases of multiple primary urinary tract related urinary cancer: 4 males and 1 females; age from 46 years old to 74 years old, with an average of 62 years old, the first primary cancer after treatment to the second primary cancer was 3 Month to 8 years, an average of 58.2 months, of which 1 case of secondary primary cancer after treatment, 2 years to regenerate the third primary cancer. The first primary cancer of renal clear cell carcinoma, bladder transitional cell carcinoma, right adrenal non-functioning cortical cancer, in the treatment of 5 years, 6 years, 3 months of colon cancer, gastric adenocarcinoma and esophageal squamous cell carcinoma ; The first primary cancer is left breast cancer, gastric cancer in the treatment of 5 years, 8 years of right renal pelvis cancer, bladder papillary carcinoma. This article also discusses the multi-primary cancer patients and immune deficiency, drug-induced chemotherapy after radiotherapy, radiation-induced dual disease and elderly patients with body resistance, decreased immunity. For patients with multiple primary cancers, due to the independence of the cancer, active surgical treatment can prolong life and improve the quality of life. Chen confirmed the first report of primary cancer of the digestive tract cancer and urothelial carcinoma occurred after the prognosis of urinary tract epithelial cancer than before the occurrence of digestive tract cancer were better. Clinicians in the diagnosis, treatment and medical history, should be alert to the existence of the second primary cancer; cases of inoperable?