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目的 探讨青年和老年乳癌的预后。方法 对作者3 所医院20 年间(1970 ~1990 年) 随诊资料完整的35 岁以下青年乳癌197 例和65 岁以上老年乳癌266 例的临床特征及预后进行回顾性分析。结果 青年和老年乳癌发病率有所上升,其5 年生存率分别为55.3%(109/197)及65.4% (174/266) ,两者间无显著性差异( P> 0.05)。原发肿瘤> 5 .0 cm ,临床Ⅲ期,腋淋巴结转移> 5 枚或妊娠、哺乳期者,青年组预后较老年组差( P < 0 .01) 。结论 提高乳癌生存率的关键是早期发现,早期综合治疗,对青年乳癌的意义尤为重要。在临床Ⅱ,Ⅲ期青年组,通过综合治疗后可提高生存率。
Objective To explore the prognosis of young and old breast cancer. Methods The clinical features and prognosis of 197 young breast cancer patients under 35 years of age and 266 breast cancer patients older than 65 years old who were followed up in the 3 hospitals of the author’s hospital for 20 years were analyzed retrospectively. As a result, the incidence of breast cancer in young and elderly patients increased. The 5-year survival rates were 55.3% (109/197) and 65.4% (174/266), respectively. There was no significant difference between the two groups (P> 0. 05). Primary tumor> 5. 0 cm, clinical stage III, axillary lymph node metastasis> 5 or pregnancy, lactation, young group than the elderly group poor (P <0. 01). Conclusion The key to improving the survival rate of breast cancer is early detection and early comprehensive treatment, which is particularly important for young breast cancer. In the clinical II and III young groups, the survival rate can be improved after comprehensive treatment.