论文部分内容阅读
目的探讨宫颈细胞学结果为不除外高度上皮内病变的不典型鳞状细胞(ASC-H)的临床意义和处理。方法 2005年1月至2010年8月在宫颈疾病诊治保健中心的134例宫颈细胞学结果为ASC-H的患者行阴道镜下活检并对结果进行分析。结果全部病例均行阴道镜下活检,诊断慢性宫颈炎44例(32.8%),CINⅠ25例(18.7%),CINⅡ27例(20.1%),CINⅢ32例(23.9%),鳞状细胞癌6例(4.5%);组织学病理证实人乳头状瘤病毒(HPV)阳性者77例,检出率(84.4%)高于阴性者(43.9%)。结论宫颈细胞学结果为ASC-H提示宫颈鳞状上皮内瘤变发生率达67.2%,阴道镜下活检对ASC-H的明确诊断和处理有重要的指导意义。
Objective To investigate the clinical significance and treatment of atypical squamous cells (ASC-H) whose cervical cytology results are not associated with intraepithelial neoplasia. METHODS: From January 2005 to August 2010, 134 patients with cervical cytology ASC-H underwent colposcopic biopsy and analyzed the results at the Cervical Disease Treatment and Treatment Center. Results All the cases underwent colposcopy biopsy, 44 cases (32.8%) diagnosed chronic cervicitis, 25 cases (18.7%) of CINⅠ, 27 cases (20.1%) of CINⅡ, 32 cases (23.9%) of CINⅢ and 6 cases of squamous cell carcinoma %). Totally 77 cases were confirmed histologically positive for human papillomavirus (HPV), the detection rate was 84.4% higher than that of negative (43.9%). Conclusions Cervical cytology results suggest that ASC-H has a 67.2% incidence of cervical squamous intraepithelial neoplasia. Colposcopy biopsy has an important guiding significance for the definite diagnosis and treatment of ASC-H.