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目的观察联合使用苦参凝胶及雌二醇凝胶治疗老年性阴道炎的疗效。方法按照随机数字表法,将100例老年阴道炎患者分为两组各50例,对照组予阴道内甲硝唑栓治疗,治疗组每晚腹部外涂雌二醇凝胶,后将苦参凝胶放入阴道后穹隆部。观察临床疗效、症状及体征改善情况,检测血清雌激素、促卵泡素水平及子宫内膜厚度。结果治疗组总有效率优于对照组(P<0.05),血清雌激素水平略升高(P<0.05),但对促卵泡素水平及子宫内膜无明显影响(P>0.05)。结论外用苦参凝胶、雌二醇凝胶治疗老年性阴道炎疗效显著。
Objective To observe the efficacy of combined use of kushen gel and estradiol gel in the treatment of senile vaginitis. Methods According to the random number table method, 100 elderly patients with vaginitis were divided into two groups of 50 cases. The control group was treated with intra-vaginal metronidazole suppository. The treatment group was given abdominal estradiol gel every night, Gel into the vaginal vaginal vault. To observe the clinical efficacy, symptoms and signs of improvement, detection of serum estrogen, follicle stimulating hormone levels and endometrial thickness. Results The total effective rate in the treatment group was better than that in the control group (P <0.05). The serum estrogen level slightly increased (P <0.05), but had no effect on the follicle stimulating hormone levels and the endometrium (P> 0.05). Conclusion External use of kushen gel, estradiol gel treatment of senile vaginitis significant effect.