免疫母细胞性淋巴结病(IBLA)也称血管免疫母细胞性淋巴结病,由Frizzera(1974)和Lukes(1975)提出。本病呈恶性淋巴瘤样的临床症状,但无恶性改变的病理学征象。IBLA的临床特征为多见于高龄者,无性别差异,症状有发热、出汗、体重减轻、全身淋巴结肿大、皮疹,皮疹呈斑丘疹,常伴有搔痒,除淋巴结肿大外,有时伴肝脾肿大。抗菌素治疗全无反应。实验室检查可见中至高度贫血,Coomb’s阳性的溶血性贫血,白细胞增多,抗淋巴球抗体阳 Immunoblastic lymphadenopathy (IBLA), also known as angioimmunoblastic lymphadenopathy, is proposed by Frizzera (1974) and Lukes (1975). The disease was malignant lymphoma-like clinical symptoms, but no signs of malignant changes in the pathology. IBLA clinical features are more common in older persons, no gender differences, the symptoms of fever, sweating, weight loss, generalized lymph nodes, rash, rash rash, often accompanied by itching, in addition to lymph nodes, sometimes with the liver splenomegaly. Antibiotic treatment no response. Laboratory tests showed moderate to high anemia, Coomb’s positive hemolytic anemia, leukocytosis, anti-lymphocyte antibody positive