复方酮康唑霜是我院应用多年的外用抗真菌药（主要由酮康唑、特美肤等成分组成），疗效确切。为保证制剂质量和疗效均衡性，采用高效液相色谱（HPLC）法对处方中主药酮康哇进行了含量测定。1试药与仪器1．1试药：二氯甲烷、乙醚均为分析纯，酮康唑对照品系英国进口（符合BP标准 Compound ketoconazole cream is our hospital for many years of topical antifungal agents (mainly composed of ketoconazole, special skin, etc.), the exact effect. In order to ensure the quality of the preparation and the balance of the curative effect, the content of ketoprofen in the prescription was determined by high performance liquid chromatography (HPLC). 1 Reagents and Instruments 1.1 Reagents: Dichloromethane, ethyl ether are analytically pure, ketoconazole reference line imported from the United Kingdom (in line with BP standards