为探讨２４ ｈ 胃内ｐＨ的节律变化，对４２ 例受试者（正常组１０ 例、功能性消化不良组２５ 例、其它组７ 例）用便携式ｐＨ 记录仪作２４ ｈ 胃内ｐＨ监测，所有受试者空腹胃液ｐＨ≤２。结果显示２４ ｈ 胃内ｐＨ值随进餐后上升＞ ４，持续２～３ｈ；夜间可出现与进餐无关的无酸波（ｐＨ＞ ４），出现率为７９％ （３３／４２），以后半夜多见。功能性消化不良组无酸波持续时间较正常组明显长，可能与病理性十二指肠胃反流有关 In order to investigate the circadian rhythm of gastric pH at 24 h, 42 patients (normal group, 25 patients with functional dyspepsia group, and 7 other patients) were monitored by intragastric pH using a portable pH logger for 24 h. All Subject fasting gastric juice pH ≤ 2. The results showed that the intragastric pH value increased more than 4 after meals, lasting for 2 to 3 hours. There was no acid wave (pH> 4) at night, which was 79% (33/42) in the stomach after midnight see. Functional dyspepsia no acid wave duration was significantly longer than the normal group may be related to pathological duodenal reflux