目的观察步长稳心颗粒与胺碘酮联用治疗急性脑梗死并心律失常的疗效及耐受性。方法将109例患者随机分为两组,治疗组54例采用步长稳心颗粒与较小剂量胺碘酮联用治疗;对照组58例应用较大剂量胺碘酮治疗,观察疗效及耐受性。结果治疗1个月后治疗组总有效率92.59%,对照组总有效率81.82%。两组间差异有统计学意义(P<0.05)。结论步长稳心颗粒与较小剂量胺碘酮联用治疗心律失常有明显疗效,更易为患者耐受。作用机制除直接抗心律失常外,还降低了血液黏度,抑制血小板聚集等作用,且无明显不良反应。 Objective To observe the curative effect and tolerance of step-stabilizing granule and amiodarone in the treatment of acute cerebral infarction and arrhythmia. Methods A total of 109 patients were randomly divided into two groups. 54 cases in the treatment group were treated with the step-stabilizing granule in combination with the smaller dose of amiodarone, and 58 cases in the control group were treated with higher-dose amiodarone. The curative effect and the tolerance were observed Sex. Results After treatment for 1 month, the total effective rate was 92.59% in the treatment group and 81.82% in the control group. The difference between the two groups was statistically significant (P <0.05). Conclusion Stable heart particles and smaller doses of amiodarone combined treatment of arrhythmia have a significant effect, more tolerable patients. In addition to direct anti-arrhythmia mechanism, but also reduces the blood viscosity, inhibition of platelet aggregation and other effects, and no significant adverse reactions.