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报告136例4种非甲状腺疾病及36例健康人TRH兴奋试验结果,其中肝硬化46例,未控制糖尿病43例,慢性肾功能不全42例,慢性肺心伴心功能不全5例,均有血清T_3水平下降,与病情严重程度及控制情况相关,差异有显著性意义。肝硬化与失代偿程度、有无伴发肝昏迷以及血清白蛋白浓度有关;未控制糖尿病与空腹血糖呈负相关;慢性肾功能不全与血清尿素氮和肌酐呈负相关,与血清白蛋白浓度呈正相关。患者血清TSH呈弱反应者为61.90～88.23％,峰值时间延迟者16.67～34.88％,提示垂体储备功能较差和(或)下丘脑功能受损。
Report of 136 cases of 4 non-thyroid disease and 36 healthy subjects TRH excited test results, including 46 cases of cirrhosis, uncontrolled diabetes 43 cases, 42 cases of chronic renal insufficiency, chronic heart failure with heart failure in 5 cases, both serum T_3 level decreased, with the severity and control of the situation, the difference was significant. Cirrhosis and degree of decompensation, with or without hepatic coma and serum albumin concentration; uncontrolled diabetes and fasting blood glucose was negatively correlated; chronic renal insufficiency and serum urea nitrogen and creatinine was negatively correlated with serum albumin concentration Was positively correlated. Serum TSH was weakly responders were 61.90 to 88.23%, peak time delay of 16.67 to 34.88%, suggesting that poor pituitary reserve function and / or impaired hypothalamic function.