~3H-标记化合物的制备、贮存和使用过程中需要测量放化纯度,而纸层析是迄今为止普遍采用的分离分析方法之一。由于~3H是软β发射体,在层析纸上的~3H样品大部分均被层析纸片所吸收。任何有窗的探测器其效率都非常低,甚至无法使用。国外对~3H类标记化合物的层析测量主要用液体闪烁探测器,或者用无窗流气正比计数器扫描。为了克服~3H-标记化合物层析样品测量的困难,使层析纸上~3H-标记化合物的分布 The ~ 3H-labeled compounds need to be measured for radiochemical purity during preparation, storage and use, and paper chromatography is one of the most widely used methods of separation and analysis to date. Since ~ 3H is a soft beta emitter, most of the ~ 3H samples on the chromatographic paper are absorbed by the chromatographic disc. Any windowed detector is inefficient and can not even be used. Chromatographic measurements of ~ 3H labeled compounds are mainly done with a liquid scintillation detector or with a windowless gas-gas proportional counter. In order to overcome difficulties in the measurement of ~ 3H-labeled compound chromatographic samples, the distribution of ~ 3H-labeled compounds on chromatographic paper