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溴克丁能降低肢端肥大症病人的生长激素(GH)水平,是治疗肢端肥大症最有效的药物。本文报道溴克丁对11例常规疗法(手术、放射或手术放射联合疗法)无效病例的治疗。所有患者治疗前的 GH 水平都增高,其中3例高于50ng/ml,其余8例低于50ng/ml。第1月口服溴克丁5mg/日,第2～4月增至10mg/日,以后根据 GH 水平调整剂量,以使 GH 周日平均水平降为10ng/ml,最大剂量可达60mg/日。如每天剂量大于5mg 时可分3次服用。观察时间为12～22个月,平均15个月。结果原血浆 GH 水平低于50ng/ml 者8例,
Bromocriptine can reduce the level of growth hormone (GH) in patients with acromegaly and is the most effective treatment for acromegaly. This article reports the efficacy of bromocriptine in the treatment of 11 cases of conventional therapy (surgery, radiation or surgical radiation combination therapy) ineffective cases. All patients had elevated GH levels before treatment, with 3 of more than 50 ng / ml and the remaining 8 less than 50 ng / ml. In the first month oral bromine 5mg / day, from February to April increased to 10mg / day, after adjusting the dose according to GH levels, GH so that the average level of Sunday reduced to 10ng / ml, the maximum dose of up to 60mg / day. If the daily dose is greater than 5mg can be divided into 3 times taking. Observation time was 12 to 22 months, an average of 15 months. The results of the original plasma GH levels below 50ng / ml in 8 cases,