为探讨急性有机磷农药中毒中间综合征（ＩＭＳ）机械通气治疗的方法及其疗效。应用机械通气治疗２１例ＩＭＳ，其中９例应用ＫＴＨ－３型呼吸机，采用容量控制模式，１２例应用Ｓｅｒｖｏ－９００Ｃ型呼吸机，采用容量控制或加压力支持，在通气过程中监测经皮血氧饱和度、血气分析、心电图、阿托品用量等并调整呼吸机参数，结果２１例中６例一次停机，１２例逐步停机，３例死亡；增加阿托品用量者通气维持时间长，减少阿托品用量者，通气维持时间短；提示机械通气是ＩＭＳ的有效治疗方法，在应用过程中及时调整呼吸机参数，减少阿托品用量，防止并发症等十分重要 To investigate the treatment of acute organophosphorus pesticide poisoning intermediate syndrome (IMS) mechanical ventilation and its efficacy. 21 cases of IMS were treated with mechanical ventilation, 9 of them were treated with KTH-3 type of ventilator, volume control mode, 12 cases of Servo-900C type of ventilator with volume control or pressure support, and monitoring of transcutaneous blood flow during ventilation Oxygen saturation, blood gas analysis, electrocardiogram, atropine dosage and so on, and adjust the ventilator parameters, the results of 21 cases of 6 cases of a shutdown, 12 cases were gradually shut down and 3 died; increase the amount of atropine ventilation to maintain a long time to reduce the amount of atropine, Ventilation to maintain a short time; prompted mechanical ventilation is an effective IMS treatment, the timely adjustment of ventilator parameters in the course of application, reduce the amount of atropine, to prevent complications is very important