伴有巨块性淋巴结肿大的窦组织细胞增生症(sinus histiocytosis、with massivelymphadenopathy,简称SHML)是一种特发性的、以双侧颌颈部淋巴结无痛性缓慢肿大为主要特点的良性病变。患者伴有发热、中性白细胞增高、血沉加速、多克隆γ-球蛋白血症等征候。本病较罕见,临床易误诊为恶性淋巴瘤。现报告1例如下。患者大,12岁。因双侧颈部肿块进行性肿大1年半,伴鼻塞、呛咳、呼吸困难2月,于1988年9月29日入院。体检:双侧颌 Sinus histiocytosis with massivelymphadenopathy (SHML) is an idiopathic benign sinus syndrome characterized by painless slow enlargement of bilateral maxillofacial lymph nodes Lesions. Patients with fever, neutrophils, ESR, polyclonal gamma-globulinmia symptoms. The disease is relatively rare, clinically misdiagnosed as malignant lymphoma. One report is as follows. Patient, 12 years old. Due to bilateral neck mass swelling 1 and a half years, with nasal congestion, choking, difficulty breathing in February, 1988 September 29 admission. Physical examination: bilateral jaw