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1 血清金属基质蛋白酶及其抑制因子分类来源及作用底物血清金属基质蛋白酶类 (ＭＭＰｓ)是一类含有锌原子的、其活性依赖于钙离子的蛋白酶 ,可以降解ＥＣＭ中的主要生物大分子。按作用底物不同主要分为五大类 (1)间质胶原酶 196 2年发现可分为成纤维细胞型 (又称 ,间质胶原
1 Serum matrix metalloproteinases and their inhibitors Classification Source and role Substance Serum Matrix metalloproteinases (MMPs) are zinc-containing proteases whose activity depends on calcium ions and can degrade major biological macromolecules in ECM. According to the role of different substrates are divided into five categories (1) interstitial collagenase 196 2 years can be divided into fibroblast type (also known as interstitial collagen