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本文报道了布洛芬-聚乙二醇(PEG)20000固体分散体的差热分析图谱.用熔融法和溶剂法制备的含不同比例PEG20000的固体分散体显示了与各相应的物理混合物相类似的DTA图谱,表明固体分散体中无固体复合物形成.两个宽的吸热峰表示了固体分散体的DTA图谱的特征.两个峰分别为布洛芬及PEG20000的熔解.当两组分比例接近于低共熔混合物组
This paper reports the differential thermal analysis of solid dispersions of ibuprofen-polyethylene glycol (PEG) 20000. Solid dispersions containing different ratios of PEG20000 prepared by the melt and solvent methods show similarities to the respective physical mixtures DTA spectra showed no solid complex formation in the solid dispersion.The two broad endotherms indicated the DTA pattern of the solid dispersion.The two peaks were the melting of ibuprofen and PEG20000 respectively.When the two components The ratio is close to the eutectic mixture group