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目的:研究茶树花对大鼠肥胖病和高脂血症的预防作用。方法:将40只大鼠分为5组,即:基础饲料组、高脂饲料组、茶树花2.5%、5%、7.5%3个剂量组。每两天测量体重和摄食量1次,24d后断头取血,测定总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)。取体脂(肾及睾丸周围脂肪)称重。结果:与基础饲料组相比,高脂饲料组大鼠体重、脂肪系数、TC、TG、LDL-C、动脉粥样硬化指数(AI)显著增加;3个剂量茶树花添加组大鼠体重、脂肪系数、TC、TG、LDL-C、AI均低于高脂饲料组,且呈显著或极显著差异;中、高剂量组大鼠体重、脂肪系数、TC、TG、LDL-C、HDL-C、AI与基础饲料组无明显差异。结论:茶树花对大鼠肥胖病和高脂血症有一定的预防作用,3个剂量组中添加5%茶树花效果最好,可开发为降脂减肥的纯天然保健食品。
Objective: To study the preventive effect of tea tree flower on obesity and hyperlipidemia in rats. Methods: Forty rats were divided into five groups: basic diet group, high fat diet group and 2.5%, 5% and 7.5% of tea tree flower. Body weight and food intake were measured once every two days. After 24 days, blood samples were taken for determination of total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol -C). Take body fat (fat around the kidney and testis) weighing. Results: Compared with the basic diet group, body weight, fat coefficient, TC, TG, LDL-C and atherosclerosis index (AI) of rats in high fat diet group increased significantly; body weight, TC, TG, LDL-C, AI were significantly lower than those in high-fat diet group, and there were significant or extremely significant differences in body weight, fat coefficient, TC, TG, LDL- C, AI and basic feed group no significant difference. Conclusion: Tea tree flower has some preventive effects on obesity and hyperlipidemia in rats. 5% tea tree flower is best in 3 dose groups, which can be developed as pure natural health food with lipid-lowering and weight-loss.