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为探讨气压损伤对内耳的病理学影响,我们开展了豚鼠内耳气压损伤的实验研究,用火棉胶包埋切片法和扫描电镜对豚鼠内耳气压损伤后的病理变化,进行了系统的观察.实验动物经过气压损伤后的内耳,最早出现的是耳蜗螺旋器(Corti氏器)的毛细胞变性,其次是支持细胞的变性.毛细胞的早期变化是听毛部分缺损,尤其是耳蜗Corti氏器的第三排外毛细胞,随着病变的加重,然后是细胞体,包括部分细胞的破坏和缺损,这些变化用扫描电镜能清楚地观察出Corti氏器表面细胞微细结构的病理变化.用火棉胶包埋切片能对耳蜗和前庭进行全面的观察.本文简略地介绍豚鼠气压损伤后内耳的一些病理变化.
In order to explore the pathological effects of barotrauma on the inner ear, we carried out an experimental study on the pressure injury of the inner ear of guinea pigs, and observed the pathological changes of the inner ear pressure of guinea pigs after trauma with barcelona embedding and scanning electron microscopy. The earliest lesions in the inner ear following air pressure injury were degeneration of the hair cells of the cochlear spiral (Corti), followed by degeneration of the supporting cells.The early changes in the hair cells were defects of the hair, especially the Corti The third row of outer hair cells, with the increase of lesions, and then the cell body, including the destruction of some cells and defects, these changes can be clearly observed by scanning electron microscopy Corti cell surface microstructure of the pathological changes. Burial section can be a comprehensive observation of the cochlea and vestibule.This article briefly introduces some of the pathological changes of the inner ear after guinea pig pressure injury.