纤维素样变性是间质疏松结缔组织及小血管壁的一种变性。病变表现为小灶状结构消失,呈细颗粒状或小条状,均质、无结构、折光性强,有纤维素样染色反应的物质。因其有退变、断裂及血管壁破坏,故也叫纤维素样坏死。病变发生机理,一般认为由于结缔组织基质变性,分解和凝集,大量粘多糖与坏死组织衍化的硷性蛋白结合形成,血浆蛋白的渗出,有人研究证实变性物质中有纤维蛋白。有人发现其中有大量Υ—球蛋白,也有抗原抗体复合物,认为与变态反应性 Cellulolytic degeneration is interstitial loose connective tissue and small blood vessel wall. Lesions showed small focal structure disappeared, was fine granular or strip, homogeneous, no structure, refractive strong, with cellulose-like staining reaction material. Because of its degeneration, rupture and destruction of the vessel wall, it is also called cellulose-like necrosis. Pathogenesis, it is generally believed that due to the degeneration, decomposition and aggregation of connective tissue matrix, a large number of mucopolysaccharide and necrotic tissue derived from the formation of alkaline protein, the exudation of plasma proteins, some studies have confirmed that there are fibrin denaturation substances. Some people found that there are a large number of γ-globulin, there are antigen-antibody complexes, that with the allergic