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本文记取并归属了二十一种以前未见文献报道的N-取代苯并氮杂冠醚化合物在氯仿中的1~H和(13)~C NMR谱,提供了一批原始数据。讨论了这批化合物中氮原子上取代基对于其1~H和(13)~C NMR行为的影响以及(胺类)苯并氮杂冠醚化合物在溶液中的构象转动问题。按其不同的NMR待性将这批新合成的化合物分成酰胺类苯并氮杂冠醚化合物(Ⅰ系列)和胺类苯并氮杂冠醚化合物(Ⅱ系列)两个系列(见图);并确认Ⅱ系列化合物在氯仿中都有所谓“稀释位移效应”,而Ⅰ系列化合物在同样的条件下不发生稀释位移效应。
Twenty-one previously reported 1H-substituted benzazepinium compounds in chloroform were recorded and assigned to provide a set of raw data. The effects of the substituents on the nitrogen atoms in these compounds on their 1 H and 13 C NMR properties and the conformational rotation of benzazepin compounds in solution were discussed. According to their different NMR desirability, the newly synthesized compounds are divided into two series (see the figure) of amide benzazepin ether compounds (Ⅰ series) and amine benzazepin ether compounds (Ⅱ series); It was also confirmed that the II series of compounds have a so-called “dilute displacement effect” in chloroform while the I series of compounds do not exhibit the diluting displacement effect under the same conditions.