过渡金属催化烯炔环化反应可以高效、快速的构建碳及杂环化合物,因此在有机合成领域得到广泛的应用.发展条件温和、以及廉价金属催化的烯炔环化反应一直是有机合成领域的研究热点之一.虽然Cu(I)配合物催化炔烃环化反应的例子已有少量报道,但使用的Cu(I)配合物催化剂中的配体难以合成并且不稳定,底物适用范围窄.因此,发现新的催化体系催化烯炔环化反应是该领域中最大的挑战之一.湖南大学化学化工学院李金恒小组以CuCl_2作为 Transition metal-catalyzed enyne cyclization can be used to build carbon and heterocyclic compounds efficiently and rapidly, so it has been widely used in the field of organic synthesis.It has been a field of organic synthesis that mild conditions and mild metal-catalyzed alkynyl cyclization However, the Cu (I) complex catalysts are difficult to synthesize and unstable because of the small number of cases reported for the Cu (I) complex catalyzed cyclization of alkynes . Therefore, it is found that the new catalytic system catalyzes cycloalkyne reaction is one of the biggest challenges in this field.Li Jinheng, School of Chemistry and Chemical Engineering, Hunan University,