198 7年 Busto首次提出“全身亚低温脑保护”的概念 ,邸采用物理手段将全身体温下降至 32～ 35℃水平 ,保护神经元避免缺血损害的方法 ,疗效与深低温等同 ,但避免了深低温的心肺并发症。从此不断进行亚低温干预新生动物缺氧缺血脑损害的实验研究 ,至今 ,关于其对脑神经的保护作 1987. Busto first proposed the concept of “whole body hypothermia brain protection.” Di physically uses physical means to lower body temperature to 32-35 ° C and protects neurons from ischemic damage. The efficacy is equivalent to that of deep hypothermia, but it is avoided Deep hypothermic cardiopulmonary complications. Since then, hypothermia intervention in neonatal animal hypoxic-ischemic brain damage experimental study, so far, on its protection for the brain