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α_2-HS 糖蛋白(A_2HSG)是一种分子量为49KD 的蛋白,其确切的生物学作用尚不清楚.据报道A_2HSG 对骨组织的钙化与吸收、体内抗感染可能具有一定作用,本文着重对血液学恶性肿瘤病人血清A_2HSG 水平及其意义进行探讨。252例患者,其中ALL 14例、ANLL 59例、CGL、CLL 各24例、CMML 15例、HD 28例、NHL 41例、骨髓纤维化(MF)及多发性骨髓瘤(MM)各18例、真性红细胞增多症(PCV)11例,另以59名健康人为对照.除进行肝功、碱性磷酸酶等多项实验室检查外,采用免疫电泳扩散法进行血清A_2HSG 测定.结果,健康对照组,血清A_2HSG 平均浓度为
α_2-HS glycoprotein (A_2HSG) is a protein with a molecular weight of 49KD, and its exact biological role is unclear. It has been reported that A_2HSG may play a role in the calcification and absorption of bone tissue and in vivo anti-infective. To study the serum A_2HSG level in patients with malignant tumor and its significance. Among 252 patients, there were 14 cases of ALL, 59 cases of ANLL, 24 cases of CGL and CLL, 15 cases of CMML, 28 cases of HD, 41 cases of NHL, 18 cases of myelofibrosis (MF) and multiple myeloma (MM) Eleven patients with polycythemia vera (PCV), and the other 59 healthy people as a control.In addition to liver function, alkaline phosphatase and other laboratory tests, the use of immune electrophoresis diffusion method serum A_2HSG determination.Results, the healthy control group , Serum A_2HSG average concentration of