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目的探讨支气管镜干预在耐多药呼吸机相关性肺炎治疗过程中的价值。方法耐多药呼吸机相关性肺炎患者78例,治疗过程中分为接受支气管镜检查治疗组(干预组)和未行支气管镜检查治疗组(对照组),比较2组血气分析变化、首次痰培养阳性率、临床肺部感染评分及病死率。结果治疗后干预组与对照组比较pH、p(O2)升高,p(CO2)降低(P<0.05);首次痰培养阳性率明显高于对照组,临床肺部感染评分、病死率明显低于对照组,差异均有统计学意义(P<0.05)。结论在耐多药呼吸机相关性肺炎患者治疗过程中早期进行支气管镜检查治疗,短期内可改善预后。
Objective To investigate the value of bronchoscopic intervention in the treatment of multidrug-resistant ventilator associated pneumonia. Methods A total of 78 patients with MDR-related pneumonia were divided into two groups: the bronchoscopy group (intervention group) and the bronchoscopy group (control group), the changes of blood gas analysis, the first sputum Culture positive rate, clinical lung infection score and mortality. Results After treatment, the levels of pH, p (O2) and p (CO2) in the intervention group were significantly lower than those in the control group (P <0.05). The positive rate of the first sputum culture was significantly higher than that of the control group. In the control group, the differences were statistically significant (P <0.05). Conclusions Bronchoscopy can be performed early in the course of treatment of patients with multidrug-resistant ventilator-associated pneumonia and may improve prognosis in the short term.