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目的观察百和清金颗粒对木火刑金型儿童感染后咳嗽的临床疗效。方法将60例符合感染后咳嗽西医诊断标准且中医辨证为木火刑金证的患儿,随机分为治疗组和对照组各30例。治疗组用百和清金颗粒每日1剂,每剂等分3份,分早、中、晚冲服,对照组根据症状选用抗过敏、化痰、抗过敏等对症治疗。疗程1周,治疗前后评定中医症候,测定中医症候积分。结果治疗组临床疗效优于对照组,总有效率治疗组为96.67%,对照组为89.65%,差异具有显著统计学意义(P<0.01)。此外,治疗组在咳嗽阵作、胸胁引痛、口干口苦、烦躁哭闹、咳痰、舌象症状改善方面均优于对照组(P<0.01)。经治疗后两组的中医症状平均积分均较治疗前下降,差异有统计学意义(P<0.01);两组间比较,差异亦有统计学意义(P<0.01)。结论百和清金颗粒在改善儿童木火刑金型感染后咳嗽等临床症状方面有较好疗效,且无明显副作用。
Objective To observe the clinical effects of Baihe Qingjin Granule on cough after infection with golden flames. Methods Sixty children with cough diagnosed as Western medicine and TCM syndromes as golden flames were randomly divided into treatment group (n = 30) and control group (n = 30). Treatment group with Baihe Qingjin granules daily 1, each dose equally divided 3, points early, middle and late blunt service, the control group according to the symptoms of anti-allergy, phlegm, anti-allergy symptomatic treatment. Treatment for 1 week, assessment of TCM symptoms before and after treatment, determination of TCM symptom score. Results The clinical efficacy of the treatment group was better than that of the control group. The total effective rate was 96.67% in the treatment group and 89.65% in the control group, with significant difference (P <0.01). In addition, the treatment group was better than the control group in the cough array, thorax and throat pain, dry mouth and mouth pain, irritability, crying, phlegm, tongue symptoms improvement (P <0.01). After treatment, the mean scores of symptoms of TCM in both groups were significantly lower than those before treatment (P <0.01). The differences between the two groups were also statistically significant (P <0.01). Conclusions Baihe Qingjin Granule has better curative effect in improving clinical symptoms such as cough after golden flare infection in children, and no obvious side effects.