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丙硫咪唑(albendazole分子式C_(12)H_(15)N_3O_2S)是广谱、高效、低毒、安全的驱蠕虫新药,为白色粉末,无臭无味,口服胶囊分人、畜用两种制剂。该药在体内代谢为亚砜和砜,抑制吸收葡萄糖而起杀虫作用;并抑制延胡索酸还原酶系统,阻碍产生ATP,使虫体无法发育生存。口服半小时后组织中浓度最高,24小时绝大部分由肾脏排出。小鼠口服LD_(50)为6012mg/kg。丙硫咪唑对人和家畜的线虫、绦虫及部分吸虫,以及肠道内、组织中的成虫、幼虫都很有效,适用于混合感染。常用剂量为400mg,一次口服,根据包括我国在内的9个国家1455人的资料,蛲虫、蛔虫、钩
Albendazole (albendazole molecular formula C_ (12) H_ (15) N_3O_2S) is a broad-spectrum, high efficiency, low toxicity and safe worm-repellent new drug. It is a white powder, odorless and tasteless. The drug is metabolized in the body as sulfoxides and sulfones, inhibit the absorption of glucose and play a pesticide; and inhibition of fumarate reductase system, hinder the production of ATP, so that parasites can not develop and survive. Oral half an hour after the highest concentration in the organization, the vast majority of 24 hours by the kidneys. Mice oral LD_ (50) 6012mg / kg. Cefazolin on human and livestock nematodes, tapeworms and some flukes, as well as the intestines, tissues of adults, larvae are very effective for mixed infections. Commonly used dose of 400mg, once orally, according to our country, including nine countries, including the information of 1455 people, pinworm, roundworm, hook