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阿片受体在胚胎发育的早期和中期出现,数量随年龄而增加,经一定时期达到成年水平。发育过程中受体亲和力不变。阿片受体和阿片肽的发生和变化基本平行。到一定年龄,受体亚型形成具有成年特征的分布。发育中如外加阿片类物质可引起受体数量减少。胚胎期的β-内啡肽和μ受体与发育有关。
Opioid receptors occur in the early and mid-embryonic development, with the number increasing with age and reaching adulthood over a period of time. Receptor affinity unchanged during development. The occurrence and changes of opioid receptors and opioid peptides are basically parallel. To a certain age, receptor subtypes form a distribution with adult characteristics. The development of opioids such as the addition can cause a decrease in the number of receptors. Embryonic β-endorphin and μ receptor and development.