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目的 :通过对各类心血管疾病患者体内锂含量的测定以探讨二者之间的关系。方法 :选择 110例各类心血管疾病患者及 31例正常人作为对照 ,抽取外周静脉血 ,测定血浆锂与红细胞内锂的含量 ,并进行统计学分析。结果 :各类心血管疾病患者红细胞内锂的含量明显低于正常对照组 (P <0 .0 1) ;随着心功能不全的逐渐加重 ,血浆锂含量亦逐渐降低。结论 :提高血浆或红细胞内微量元素锂的含量 ,可望降低心血管疾病的发病率及改善心脏功能。
Objective: To explore the relationship between the two in the determination of lithium in patients with various cardiovascular diseases. Methods: A total of 110 patients with cardiovascular diseases and 31 normal controls were selected as control. Peripheral venous blood was collected for determination of lithium in plasma and erythrocytes, and statistical analysis was performed. Results: The content of lithium in erythrocytes of patients with various cardiovascular diseases was significantly lower than that of the normal control group (P <0.01). With the gradual increase of cardiac insufficiency, the plasma lithium content also decreased gradually. Conclusion: Increasing the content of trace element lithium in plasma or erythrocytes is expected to reduce the incidence of cardiovascular diseases and improve cardiac function.