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目的探讨心肌肌钙蛋白Ｉ（ｃＴｎＩ）、肌红蛋白（Ｍｂ）在急性心肌梗塞早期诊断中的价值。方法对胸痛发作后４～６ｈ的２７例急性心肌梗塞（ＡＭＩ）患者，２５例健康者，２８例非急性心肌梗塞患者的血清心肌肌钙蛋白Ｉ（ｃＴｎＩ）和肌红蛋白（Ｍｂ）进行测定。结果ＡＭＩ组血清ｃＴｎＩ值明显高于健康组及其它对照组，差异有显著性（Ｐ＜００５）ＡＭＩ组Ｍｂ值显著高于正常值，除骨骼肌损伤组Ｍｂ有明显开高外，其它对照组测定值均在正常范围以内，与ＡＭＩ组有明显差异（Ｐ＜００１）。ｃＴｎＩ及Ｍｂ的灵敏性明显高于ＣＫ－ＭＢ。结论ｃＴｎＩ是诊断ＡＭＩ较理想的指标，同时测Ｍｂ可对ＡＭＩ的早期诊断提供一种较ＣＫ－ＭＢ更为经济、快速、可靠的生化指标，具有临床应用价值。
Objective To investigate the value of cardiac troponin I (cTnI) and myoglobin (Mb) in the early diagnosis of acute myocardial infarction. Methods Serum cardiac troponin I (cTnI) and myoglobin (Mb) were measured in 27 patients with acute myocardial infarction (AMI), 25 healthy subjects and 28 patients with non-acute myocardial infarction 4 to 6 hours after the onset of chest pain. . Results The serum cTnI level in AMI group was significantly higher than that in healthy group and other control groups (P <005). The Mb value in AMI group was significantly higher than that in normal group, except Mb in skeletal muscle injury group was significantly higher The control group measured values were within the normal range, and AMI group were significantly different (P <0 01). The sensitivity of cTnI and Mb was significantly higher than CK-MB. Conclusion cTnI is an ideal indicator for the diagnosis of AMI. Simultaneously measuring Mb can provide a more economical, rapid and reliable biochemical index for the early diagnosis of AMI, which has clinical value.