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目的:观察消旋卡多曲联合蒙脱石散治疗小儿轮状病毒肠炎的临床疗效。方法:将86例轮状病毒肠炎患儿随机分为两组,对照组43例采用蒙脱石散治疗,观察组43例采用消旋卡多曲联合蒙脱石散治疗,比较观察两组的临床疗效、退热、止泻时间和总疗程。结果:观察组的总有效率明显高于对照组(P<0.05)。观察组的平均退热时间、平均止泻时间和总疗程时间均明显短于对照组(P<0.05)。两组在治疗过程中均未发生明显不良反应。结论:消旋卡多曲联合蒙脱石散对小儿轮状病毒肠炎进行治疗,能够明显提高临床疗效,加快患儿退热和止泻,缩短病程,且不良反应少,是一种安全、有效的治疗方案。
Objective: To observe the clinical efficacy of racecadotril combined with montmorillonite in the treatment of pediatric rotavirus enteritis. Methods: 86 cases of rotavirus enteritis were randomly divided into two groups, the control group of 43 patients treated with montmorillonite, the observation group of 43 patients treated with racecadotril combined with montmorillonite powder, the two groups were compared Clinical efficacy, fever, antidiarrheal time and the total course of treatment. Results: The total effective rate in observation group was significantly higher than that in control group (P <0.05). The average antipyretic time, average antidiarrheal time and total duration of treatment in the observation group were significantly shorter than those in the control group (P <0.05). No significant adverse reactions occurred in both groups during the course of treatment. Conclusion: Racecadotril combined with montmorillonite powder for the treatment of pediatric rotavirus enteritis can significantly improve the clinical efficacy, to speed up children with antipyretic and antidiarrheal, shorten the course of the disease, and less adverse reactions, is a safe and effective Treatment program.