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五羟黄酮和flavopiridol都是黄酮类化合物,影响各种类型细胞的氧化、增生和凋亡,美国的Liesveld JL等观察了这类药物对急性髓性白血病细胞和正常祖细胞的作用。 五羟黄酮和flavopiridol都能抑制不同急性髓性白血病细胞系(AML)和不同亚型AML中新鲜分离的AML原始细胞的生长和存活力;抑制正常
Quercetin and flavopiridol are flavonoids that affect the oxidation, proliferation and apoptosis of various types of cells. Liesveld JL in the United States observed the effect of these drugs on acute myeloid leukemia cells and normal progenitor cells. Both quercetin and flavopiridol inhibited the growth and viability of freshly isolated AML blasts in different acute myeloid leukemia cell lines (AML) and in different subtypes AML; inhibited normal