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多发性骨髓瘤(以下简称MM)系免疫细胞增殖性疾病,以浆细胞在骨髓中瘤性浸润为其特征。病因未明。本病在国内报导日见增多,现将我院1974～1984年10月间共收治的19例(均为初诊)报告如下。一、临床资料 1.本组病例男性9例,女性10例,男:女=0.9:1。发病年龄36～64岁,平均50岁。 2.主要症状与体征:19例中有骨痛者15例占78.9％,发热(均并发肺部感染)5例占26.3％,贫血13例占68.4％,局部肿块3例占15.8％,自发性骨折5例占26.3％,出血2例占10.5％,肝大14例占73.7％,脾大1例占5.3％,淋巴结肿大2例占10.5％。 3.实验室检查: 血常规:红细胞45～415万,平均245万,其中<100万者2例,101～200万者5例,
Multiple myeloma (hereinafter referred to as MM) is an immune cell proliferative disease, characterized by plasmacytoid tumor infiltration in the bone marrow. Etiology is unknown. The disease reported in the country increasing day by day, now our hospital from 1974 to October 1984 were treated 19 cases (both for the first visit) are reported as follows. First, the clinical data 1. This group of 9 males and 10 females, male: female = 0.9: 1. Age 36 to 64 years old, average 50 years old. 2 main symptoms and signs: 19 cases of bone pain in 15 cases accounted for 78.9%, fever (both concurrent lung infection) in 5 cases accounted for 26.3%, anemia in 13 cases accounted for 68.4%, 3 cases of local mass in 15.8%, spontaneous 5 cases of fracture accounted for 26.3%, bleeding in 2 cases accounted for 10.5%, 14 cases of hepatomegaly accounted for 73.7%, 1 case of splenomegaly accounted for 5.3%, 2 cases of lymph node enlargement accounted for 10.5%. 3. Laboratory tests: blood: 45 to 415 million red blood cells, an average of 2.45 million, of which <1 million in 2 cases, 10 to 2 million in 5 cases,