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为确定组织学证实的绒膜羊膜炎的早产孕妇(无临床表现)的血清细胞因子水平作为诊断指标,是否优于常规指标如C-反应蛋白(CRP),白细胞计数,并与无绒毛膜羊膜炎的早产者作对照,对29例孕龄22～34周早产孕妇,在分娩时取其静脉血测定白介素6(IL-6),白介素8(IL-8),CRP,单核细胞趋化性和活化因子(MCAF),可溶性自介素6受体(sIL-6R),同时行白细胞计数。分娩后取小块胎盘组织行组织病理学检查确定有无绒毛膜羊膜炎,并按Blanc分类法确定绒毛膜羊膜炎的严重程度。 结果29例中胎盘组织学检查证实18例有绒膜羊膜炎,余11例无(对照组)。两组孕妇年龄,孕、产次,胎膜破裂例数,孕龄,新生儿出生时体重及Ap
To determine whether serum cytokines levels in histologically confirmed preterm prematurity (non-clinical) women with chorioamnionitis as diagnostic criteria are superior to conventional indicators such as C-reactive protein (CRP), leukocyte count, 29 cases of pregnant women with gestational age of 22-34 weeks were measured with venous blood before and after delivery for determination of interleukin 6 (IL-6), interleukin 8 (IL-8), CRP, monocyte chemotaxis Sex and Activation Factor (MCAF), Soluble Interleukin 6 Receptor (sIL-6R), Simultaneous White Blood Cell Count. Small pieces of placenta from childbirth after histopathological examination to determine the presence or absence of chorioamnionitis, and Blanc classification to determine the severity of chorioamnionitis. Results Twenty-nine cases of placenta histological examination confirmed 18 cases of chorioamnionitis, and the remaining 11 cases without (control group). Two groups of pregnant women age, pregnancy, parity, cases of rupture of membranes, gestational age, newborn birth weight and Ap