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目的:调查了解埃博拉病毒病(EVD)疫情暴发期间其他地方性传染病在疫区的感染情况。方法:对塞拉利昂EVD疫情暴发期间,发热患者血液标本中EVD、疟疾、伤寒和获得性免疫缺陷综合征(AIDS)等传染病的抗原或抗体进行定性检测。结果:疑似EVD 57例中,EVD核酸检测阳性率为40.4%,疟疾全抗体检测阳性率为29.8%,伤寒抗体检测阳性率为5.3%;埃博拉病毒(EBOV)核酸检测阳性100例中人类免疫缺陷病毒(HIV)全抗体(IgG、IgM和IgA)筛查阳性标本3例,而在EBOV核酸检测阴性的100例中HIV全抗体阳性24例,EBOV核酸检测阴性标本的HIV阳性率显著高于EBOV核酸检测阳性标本(P<0.05)。结论:EVD疫情暴发期间,疫区的其他地方性烈性传染病仍处于高发状态,应高度重视相应防控措施的开展。
Aims: To investigate the prevalence of other endemic diseases in endemic areas during the outbreak of Ebola virus disease (EVD). Methods: The antigen or antibody of infectious diseases such as EVD, malaria, typhoid fever and acquired immunodeficiency syndrome (AIDS) in blood samples of febrile patients during the outbreak of EVD in Sierra Leone were qualitatively detected. Results: In 57 cases of suspected EVD, the positive rate of EVD nucleic acid detection was 40.4%, the positive rate of malaria antibody detection was 29.8%, the detection rate of typhoid fever antibody was 5.3%, and that of Ebola virus (EBOV) Immunosuppressive virus (HIV) whole antibody (IgG, IgM and IgA) screening positive specimens in 3 cases, while in EBOV nucleic acid test negative 100 cases of HIV full antibody positive in 24 cases, EBOV nucleic acid test negative specimens HIV positive rate was significantly higher Positive samples were detected by EBOV nucleic acid (P <0.05). Conclusion: During the outbreak of EVD, other endemic and contagious diseases in the endemic areas are still in a high status, and the corresponding prevention and control measures should be paid great attention to.