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目的了解四川省肾综合征出血热(HFRS)疫情及宿主动物动态,为HFRS的防制提供科学依据。方法收集全省2007-2009年疫情资料;在监测点采用夹夜法捕鼠,将鼠肺冷冻切片,用免疫荧光法检测汉坦病毒抗原。结果 2007-2009年全省累计发病284例,死亡2例,主要发病地区为凉山州、南充市、广安市和达州市;在凉山州盐源县、达州市开江县和南充市3个监测点共捕获鼠10种2046只,总鼠密度10.29%,居民区以褐家鼠和小家鼠为优势鼠种,野外以四川短尾鼩和高山姬鼠为优势鼠种。鼠间汉坦病毒带病毒率为2.22%。结论褐家鼠和黑线姬鼠仍是四川省HFRS的主要宿主动物,盐源县为家鼠型出血热疫区,四川省的其他发病地区为以姬鼠型为主的混合型疫区。监测结果提示四川省今后2~3年本病可能仍将在低发状态波动,今后应继续加强监测工作。
Objective To understand the epidemic situation and host animal dynamics of hemorrhagic fever with renal syndrome (HFRS) in Sichuan Province and provide a scientific basis for the prevention and control of HFRS. Methods The epidemic data of the province from 2007 to 2009 were collected. At the monitoring site, mice were caught by the method of catching the night and the rat lungs were frozen and sectioned. The antigens of the hantavirus were detected by immunofluorescence. Results A total of 284 cases and 2 deaths were reported in the province from 2007 to 2009. The main areas of infection were Liangshan Prefecture, Nanchong City, Guang’an City and Dazhou City; three were monitored in Yanyuan County of Liangshan Prefecture, Kaijiang County of Dazhou City and Nanchong City A total of 2046 species of 10 species were captured, with a total rodent density of 10.29%. Rattus norvegicus and Mus musculus were the dominant species in the residential area. In the field, the dominant species were Brachychneumonidae and Apodemus agrarius. Hantaan virus was 2.22%. Conclusion Rattus norvegicus and Apodemus agrarius are still the main host animals of HFRS in Sichuan Province. Yanyuan County is a hamster-swine hemorrhagic fever epidemic area in Sichuan province. Other epidemic areas in Sichuan Province are mainly of the agouti-type mixed epidemic area. Monitoring results suggest that in the next 2-3 years in Sichuan Province, the disease may still fluctuate in a low state, and the monitoring work should continue to be strengthened in the future.