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目的分析比较2型糖尿病(T2MD)患者与健康人群血清中胰高血糖素样肽2(GLP-2)含量,探究两者的相关性。方法用ELISA试剂盒检测2型糖尿病患者和正常人血清中GLP-2含量。结果糖尿病患者血清中GLP-2含量显著低于正常人群(P﹤0.001)),不同性别、年龄、病史以及血糖值的糖尿病患者间GLP-2含量具有一定的趋向性,但差异并无统计学意义。结论 2型糖尿病患者血清中GLP-2含量低于正常人。
Objective To compare and analyze the serum levels of glucagon-like peptide 2 (GLP-2) in patients with type 2 diabetes mellitus (T2MD) and healthy people, and to explore their correlation. Methods Serum GLP-2 levels in patients with type 2 diabetes mellitus and normal controls were measured by ELISA kit. Results The GLP-2 level in serum of diabetic patients was significantly lower than that of normal subjects (P <0.001). The GLP-2 content in diabetic patients with different gender, age, medical history and blood glucose level had a certain trend, but the difference was not statistically significant significance. Conclusion Serum GLP-2 levels in patients with type 2 diabetes are lower than those in normal people.