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缺氧增加气道阻力,但对流速的影响尚无研究。如果在既定肺容量,肺的弹性回缩压(elastic recoilpressure of lung,P_(EL))保持恒定,则气道阻力降低将引起流速增加。这种改变可藉最大呼气流速-容量(MEFV)曲线加以测定。同时采用氮(He)和 O_2低密度混合气还可以确定阻塞的部位。本文报道慢性阻塞性肺疾病(COPD)患者呼吸30％O_2对流速的作用及定位。研究对象为12例静息时有低氧血症的严重 COPD患者。摄入支气管舒张剂后用力肺活量(FVC)、第1
Hypoxia increases airway resistance, but there is no study on the effect of flow rate. If the lung’s elastic recoil pressure of lung (P EL) remains constant at a given lung capacity, a decrease in airway resistance will cause an increase in flow rate. This change can be measured by the maximum expiratory flow-volume (MEFV) curve. At the same time using nitrogen (He) and O_2 low density mixture can also determine the obstruction of the site. This article reports the effect and localization of breathing 30% O_2 on flow rate in patients with chronic obstructive pulmonary disease (COPD). The subjects were 12 patients with severe COPD who had hypoxemia at rest. After taking bronchodilator, forced vital capacity (FVC), the first