裸鼠是建立肿瘤模型的良好动物品系，以往大多是用能传代培养的大肠癌细胞株建立的人大肠癌裸鼠模型，本研究采用病人的肿瘤组织建立了三组人大肠癌棵鼠移植模型。材料和方法一．动物BALB／C（＂u／nu）棵小鼠购自中国科学院上海实验动物研究所，SPF级，鼠龄4～8周，体重15～25 Nude mice are good animal strains for establishing tumor models. In the past, most of them were human colorectal cancer nude mice models established by passaging cultured colorectal cancer cell lines. In this study, three groups of human colorectal cancer transplants were established using patient’s tumor tissues. model. Materials and methods Animal BALB/C (“u/nu”) mice were purchased from the Shanghai Institute of Experimental Animals, Chinese Academy of Sciences, SPF grade, 4 to 8 weeks of age, weight 15 to 25