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据2011年10月3日HuY(Proc Natl Acad Sci USA,2011 Oct 3)报道,美国研究人员日前发现一种有望用于检测亨廷顿病的生物标志物,这将使医生有机会及时了解该病进程并寻找新疗法。作为一种神经退行性疾病,亨廷顿病目前没有有效疗法。美国马萨诸塞总医院和布里格姆妇科医院的研究人员分析了亨廷顿病患者、其他神经退行性疾病患者和健康人等共计119例志愿者的血样后发现,与其他人相比,亨廷顿病患者血液中表达了更高水平的H2AFY基因,超出普通人水平1.6倍。
According to a report by HuY (Proc Natl Acad Sci USA, Oct. 3, 2011) on Oct. 3, 2011, US researchers have recently discovered a biomarker that is expected to be used to detect Huntington’s disease. This will give doctors a chance to learn about the progress of the disease And look for new therapies. As a neurodegenerative disease, there is currently no effective treatment for Huntington’s disease. Researchers at the Massachusetts General Hospital and Brigham and Women’s Hospital in the United States analyzed the blood samples of a total of 119 volunteers, including Huntington’s disease patients, other neurodegenerative diseases and healthy subjects, and found that in the blood of patients with Huntington’s disease Expressed a higher level of H2AFY gene, 1.6 times more than the average human level.