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目的探讨高龄老年腔隙性脑梗死患者总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白-胆固醇(HDL-C)、低密度脂蛋白-胆固醇(LDL-C)水平变化及临床意义。方法回顾性调查了160例≥60岁老年腔隙性脑梗死患者,其中≥80岁组(80~100岁)71例,<80岁组(60~79岁)89例,测定两组血TC、TG、HDL-C、LDL-C值,对比分析两组各项检测指标。结果≥80岁组HDL-C水平较<80岁组降低,差异有统计学意义(P<0.05);≥80岁组血清中TC、TG、LDL-C与<80岁组对比,差异无统计学意义(P>0.05)。结论血HDL-C与高龄老年人腔隙性脑梗死的发生有关,监测高龄老人血HDL-C对预防腔隙性脑梗死是有必要的。
Objective To investigate the changes of total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-C) and low density lipoprotein cholesterol (LDL-C) in elderly patients with lacunar infarction significance. Methods A total of 160 patients with lacunar infarction ≥60 years old were retrospectively studied. Among them, 71 cases were ≥80 years old (80 ~ 100 years old) and 89 cases were aged <80 years old (60 ~ 79 years old) , TG, HDL-C, LDL-C values, comparative analysis of two groups of test indicators. Results The level of HDL-C in the group of ≥80 years old was lower than that in the group of <80 years old, the difference was statistically significant (P <0.05). The TC, TG, LDL-C levels in the group of ≥80 years old were not statistically different Significance (P> 0.05). Conclusion Serum HDL-C is associated with the occurrence of lacunar infarction in the elderly. It is necessary to monitor HDL-C in the elderly to prevent lacunar infarction.