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目的了解邯郸市2008-2011年疑似预防接种异常反应(adverse events following immunization,AEFI)报告情况,为更好地提高预防接种服务质量提供依据。方法将2008-2011年邯郸市AEFI监测数据导入Excel表后进行整理分析。结果 AEFI病例报告有地区差异性,全年各月均有报告,主要在5～8月。8 165例AEFI中≤1岁年龄组报告例数最多,共6 963例(85.28%),其中3～6月龄报告例数最多(77.16%);报告病例中接种后24h发生反应的4377例(53.61%);AEFI病例以一般反应为主,共7 615例(93.26%),主要为发热/红肿/硬结7 559例(99.26%);报告病例中治愈6 955例(85.18%)、好转1 184例(14.5%)、出现后遗症和死亡15例(0.19%)、不详11例(0.13%)。结论开展预防接种后出现的AEFI回顾性调查,全面分析发生的原因,对今后避免和处理类似事件有重要意义。
Objective To understand the report on the occurrence of adverse events following immunization (AEFI) in Handan from 2008 to 2011 and provide the basis for better quality of vaccination services. Methods The AEFI monitoring data of Handan City from 2008 to 2011 were imported into Excel and analyzed. Results There were regional differences in the reporting of AEFI cases, with reports for all months of the year, mainly from May to August. 8 165 cases of AEFI ≤ 1 years old reported the largest number of cases, a total of 6 963 cases (85.28%), of which 3 to 6 months of age reported the largest number of cases (77.16%); report cases in 24 hours after inoculation reaction of 4377 cases (53.61%). AEFI cases were mainly general reactions, with a total of 7 615 cases (93.26%), mainly 7 559 cases (99.26%) with fever / inflamed / indurated disease; 6 955 cases (85.18%) were cured in the reported cases, 1 184 cases (14.5%), sequelae and death occurred in 15 cases (0.19%), 11 cases were unknown (0.13%). Conclusions The AEFI retrospective investigation after vaccination is carried out and a comprehensive analysis of the causes is of great significance for avoiding and handling similar incidents in the future.