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目的:探讨胎儿不良结局与妊娠合并症并发症的关系。方法:选择2009年2月～2011年2月分娩发生胎儿不良结局且同意做胎盘和脐带病理检测的孕妇124例,结合其病史,分析不良结局的发生原因,并以120例正常新生儿胎盘及脐带作为病理检查的对照组进行对比研究。结果:接受胎盘和脐带病理检测的124例孕妇中胎盘及脐带的病理改变者112例,发生率为90.32%(112/124),其中发生绒毛纤维蛋白样坏死71例(55.65%)、绒毛合体细胞增生47例(37.90%)、绒毛血管扩张44例(35.48%)、脐带血管堵塞39例(31.45%)、绒毛水肿37例(29.84%)、绒毛血管狭窄32例(25.80%)、脐带血管炎27例(21.77%)、绒毛发育不良12例(9.68%);绒毛纤维蛋白样坏死发生率、绒毛合体细胞增生发生率、绒毛血管扩张发生率、脐带血管堵塞发生率、绒毛水肿发生率、绒毛血管狭窄发生率、脐带血管炎发生率、绒毛发育不良发生率,病例组明显高于对照组(P<0.05)。结论:胎盘、脐带的病理改变与妊娠合并症和并发症息息相关,所以在妊娠期间应密切关注各类并发症的出现,并及时实施应对措施,以减少不良妊娠结局的发生。
Objective: To investigate the relationship between fetal adverse outcomes and complications of pregnancy complications. Methods: One hundred and twenty-four pregnant women who had unwanted fetal outcomes and who agreed to do pathological examination of placenta and umbilical cord from February 2009 to February 2011 were enrolled. A total of 124 pregnant women with placenta and umbilical cord were selected for the study. The causes of adverse outcomes were analyzed. Umbilical cord as a control group for pathological examination were compared. Results: The pathological changes of placenta and umbilical cord in 124 pregnant women receiving placenta and umbilical cord pathology were detected in 112 cases (90.32%, 112/124), including 71 cases (55.65%) of fibrinous necrosis, 47 cases (37.90%) had hyperplasia, 44 cases (35.48%) villus dilation, 39 cases (31.45%) umbilical cord occlusion, 37 cases villus edema (29.84%), 32 cases villus stenosis (25.80% Inflammation in 27 cases (21.77%), villous dysplasia in 12 cases (9.68%); the incidence of villous fibrinoid necrosis, the incidence of villous syncytial cell hyperplasia, the incidence of villus dilation, umbilical cord occlusion, villus edema, The incidence of villus stenosis, umbilical vasculitis and villous dysplasia were significantly higher in the case group than in the control group (P <0.05). Conclusion: The pathological changes of placenta and umbilical cord are closely related to complications and complications during pregnancy. Therefore, during pregnancy, we should pay close attention to the occurrence of various complications and promptly implement measures to reduce the incidence of adverse pregnancy outcomes.