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目的 :比较异丙酚加不同剂量氯胺酮用于人工流产的麻醉效果。方法 :80例患者随机分为对照组、K1组、K2组、K3组 4组 ,分别作全麻诱导 ,对照组采用 1%异丙酚 2 0mg/kg ,其余 3组分别采用 1%氯胺酮 0 1mg/kg+ 1%异丙酚 1 9mg/kg ,1%氯胺酮 0 2mg/kg + 1%异丙酚 1 8mg/kg ,1%氯胺酮 0 3mg/kg + 1%异丙酚 1 7mg/kg。比较各组诱导前后的BP、完全苏醒时间及麻醉优良率。结果 :K2 ,K3组诱导后BP与对照组比较差异有显著意义 (P <0 0 5 ) ,K3组麻醉优良率与对照组比较差异有显著意义 (P <0 0 5 )。结论 :异丙酚麻醉时加入 0 2～ 0 3mg/kg氯胺酮可以有效防止异丙酚的降压作用 ,且能提高人工流产的麻醉效果。
OBJECTIVE: To compare the anesthetic effect of propofol plus different doses of ketamine for induced abortion. Methods: Eighty patients were randomly divided into control group, K1 group, K2 group and K3 group, which were induced by general anesthesia. The control group was treated with propofol 20 mg / kg, and the other three groups were treated with 1% ketamine 0 1 mg / kg + 1% propofol 1 9 mg / kg, 1% ketamine 0 2 mg / kg + 1% propofol 1 8 mg / kg, 1% ketamine 0 3 mg / kg + 1% propofol 1 7 mg / kg. Before and after induction of BP compared with each group, complete recovery time and anesthesia excellent rate. Results: There was significant difference between BP and control group after K2 and K3 induction (P <0 05). There was significant difference between the K3 group and the control group (P 0.05). CONCLUSION: When propofol is added, anesthesia with 0 2 ~ 0 3 mg / kg ketamine can effectively prevent the hypotensive effect of propofol and can improve the anesthetic effect of induced abortion.