An individual’s diet appears to have a profound impact on the health of his/her offspring as recent studies indicate that offspring can inherit metabolic disorders from their fathers[1].However,it remains unclear what factors in the sperm are responsible for the intergenerational inheritance of paternally acquired traits. An individual’s diet appears to have a profound impact on the health of his / her offspring as recent studies indicate that offspring can inherit metabolic disorders from their fathers [1] .However, it remains unclear what factors in the sperm are responsible for the intergenerational inheritance of paternally acquired traits.