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慢性粒细胞性白血病急性变(简称慢粒急变)为慢粒终末期的主要表现,治疗效果差,死亡率高。因此延长和控制慢粒急变是当前治疗中的主要研究课题。本文对我院收治的52例慢粒急变的细胞类型与临床治疗作一简要分析,以便今后更合理的治疗,提高慢粒急变的缓解率。一、慢粒急变的诊断条件 1.有慢粒的既往病史;2.外周血中原始细胞和/或早幼细胞>10％;3.骨髓中原始细胞和/或早幼细胞>15％;4.临床症状恶化,如脾脏急剧肿大,贫血加重,有出血倾向,白细胞数增多,治疗无效等。其中以2、3条为主要条件。
Acute chronic myelogenous leukemia (referred to as CML acute) is the main manifestation of CML, the treatment effect is poor, high mortality. Therefore, to prolong and control CML acute abruption is the main research topic in current treatment. This article admitted to our hospital 52 cases of acute myeloid cell types and clinical analysis of a brief analysis for the future more reasonable treatment to improve the rate of mitochondrial abruption. First, the diagnostic criteria for CML 1. Have a history of CML; 2. 10% of blasts and / or blast cells in peripheral blood; 3. 15% of blasts and / or blast cells in bone marrow; 4. Clinical symptoms such as rapid splenomegaly, anemia, bleeding tendency, increased white blood cell count, treatment ineffective. Of which 2,3 as the main condition.