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目的 :探讨难治性癫的脑电图 (EEG)特点与病因。方法 :对 78例难治性癫患者的常规EEG和头颅磁共振成像 (MRI)检查资料进行分析。结果 :EEG上波检出率仅为 2 8% ,慢波异常率则高达 6 8%。其中不同发病年龄组 (<14岁和≥ 15岁 )和不同病程组 (<10年和≥ 10年 )的样波检出率和慢波异常率比较 ,差异均有极显著意义 (P <0 .0 0 0 1)。而不同发作类型组、头MRI(- )和头MRI(+)组的样波检出率和慢波异常率比较 ,差异无显著意义 (P <0 .0 5 )。借助头颅MRI检查 ,发现难治性病因主要是大脑发育不全、脑外伤和海马硬化等。结论 :难治性癫的EEG以慢波异常增多 ,样放电减少为特点 ,并且与发病年龄、病程长短有着密切关系。故常规EEG检查价值不大 ,应行Video -EEG监测和MRI检查 ,以便尽早发现致源和难治性病因
Objective: To investigate the characteristics and causes of electroencephalography (EEG) in refractory epilepsy. Methods: The data of routine EEG and cranial magnetic resonance imaging (MRI) in 78 patients with refractory epilepsy were analyzed. Results: The detection rate of EEG wave was only 28% and the rate of slow wave anomaly was as high as 68%. Among them, the differences of the S-wave and S-wave rates in different age groups (<14 and ≥ 15 years) and in different course groups (<10 and ≥ 10 years) were significantly different (P < 0 .0 0 0 1). However, there was no significant difference in the detection rate of S wave and the rate of S wave in different types of seizures, head MRI (-) and head MRI (+) group (P <0.05). With the help of skull MRI examination, it is found that the main causes of refractory cerebral hypoplasia, brain trauma and hippocampal sclerosis. Conclusion: The EEG of refractory epilepsy is characterized by an increase of slow wave anomaly and a decrease of amalgam discharge, and is closely related to the age of onset and the duration of the disease. So the value of conventional EEG examination is not large, should be performed Video-EEG monitoring and MRI examination in order to find the source of early and refractory causes